fa مدل‌یابی روابط ساختاری ولع مصرف بر اساس سیستم‌های مغزی/رفتاری با نقش میانجی اجتناب تجربه‌ای در افراد وابسته به مواد مخدر تحت درمان نگهدارنده با متادون شهر شیراز روان‌پزشکی قانونی Forensic Psychiatry مقاله پژوهشی Research Article <span style="font-size:10pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Aptos,sans-serif"><b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">مقدمه:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">اعتیاد می‌تواند تحت تأثیر سازوکارهای مغزی و با میانجی‌گری استرس‌های محیطی و درونی تداوم یابد<b>. </b>پژوهش حاضر با هدف بررسی مدل‌یابی روابط ساختاری ولع مصرف بر اساس سیستم‌های مغزی/رفتاری با نقش میانجی اجتناب تجربه‌ای در افراد وابسته به مواد مخدر تحت درمان نگهدارنده با متادون بود.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Aptos,sans-serif"><b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">روش‌:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">روش توصیفی-همبستگی برمبنای معادلات ساختاری بود. جامعۀ آماری تمامی افراد وابسته به مواد مخدر تحت درمان نگهدارنده با متادون ( ۱۴۰5- 1404) بود. بر مبنای دیدگاه کلاین (2023)، برای دستیابی به برآوردهای پایا، به ازای هر پارامتر آزاد دست‌کم ۱۰ نفر یا حداقل ۲۰۰ نمونه لازم است؛ ازاین‌رو 280 نفر(18 تا 60 سال) در مرکز </span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">MMT</span></span><span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> دولتی به روش نمونه‌گیری غیرتصادفی‌ هدفمند انتخاب شدند. شرکت‌کنندگان پرسشنامه‌های </span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">ولع مصرف سوموزا&nbsp; و همکاران (1995)، سیستم</span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">‌</span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">های مغزی / رفتاری کارور و وایت&nbsp; (1994) و پذیرش و عمل (اجتناب تجربه‌ای) بوند و همکاران (2011) </span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">را تکمیل نمودند. تحلیل داده‌ها با استفاده از مدل‌یابی معادلات ساختاری با نرم‌افزارهای </span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">SPSS26</span></span><span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> و </span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Amos24</span></span><span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> انجام شد.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Aptos,sans-serif"><b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">نتایج: </span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">نتایج نشان داد که </span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">بازداری مغزی/رفتاری (63/0</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">=</span></span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">(</span></span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">&beta;</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">، فعال‌ساز مغزی/رفتاری (62/0</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">=</span></span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">(</span></span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">&beta;</span></span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">و </span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">اجتناب تجربه‌ای&nbsp; </span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">(50/0</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">=</span></span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">(</span></span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">&beta;</span></span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">اثر مستقیم بر ولع مصرف دارند. همچنین بازداری مغزی/رفتاری (53/0</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">=</span></span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">(</span></span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">&beta;</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black"> و</span></span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">فعال‌ساز مغزی/رفتاری (59/0</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">= </span></span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">(</span></span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">&beta;</span></span></span><span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black"> اثر مستقیم بر اجتناب تجربه‌ای دارند.</span></span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">در اثرات غیرمستقیم<b> </b>تحلیل اثرات غیرمستقیم نشان داد که بازداری مغزی/ (80/0</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">=</span></span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">(</span></span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">&beta;</span></span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">و فعال‌ساز مغزی/رفتاری(79/0</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">=</span></span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">(</span></span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">&beta;</span></span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">از طریق اجتناب تجربه‌ای بر ولع مصرف اثر غیرمستقیم معناداری دارند</span></span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">.</span></span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">(001/0</span></span></span><span dir="LTR" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">p</span></span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"><</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"><span style="color:black">)</span></span></span><b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">. &nbsp;</span></span></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Aptos,sans-serif"><b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">نتیجه‌گیری: </span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">سیستم‌های مغزی/رفتاری از طریق افزایش اجتناب تجربه‌ای، منجر به تشدید ولع مصرف در افراد وابسته به مواد تحت درمان با متادون می‌شوند. </span></span></span></span></span></span></span><br> &nbsp; <span style="font-size:10pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:Aptos,sans-serif"><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Introduction:</span></span></b> <span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Addiction can be influenced by brain mechanisms and may persist through the mediation of environmental and internal stressors. The present study aimed to investigate the structural modeling of the relationships between craving and behavioral/motivational brain systems, with the mediating role of experiential avoidance, in individuals with opioid dependence undergoing methadone maintenance treatment.</span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:Aptos,sans-serif"><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Method:</span></span></b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""> The present study was descriptive-correlational based on structural equations. The statistical population consisted of all individuals with opioid dependence undergoing methadone maintenance treatment (2025&ndash;2026). Based on Klein&rsquo;s (2023) perspective, to achieve reliable estimates, at least 10 participants per free parameter or a minimum of 200 samples are required; therefore, 280 participants (aged 18 to 60 years) were selected from a governmental MMT center using non-probability purposive sampling. Participants completed the Somoza et al. (1995) Craving Questionnaire, the Behavioral/Motivational Brain Systems questionnaire by Carver and White (1994), and the Acceptance and Action Questionnaire (Experiential Avoidance) by Bond et al. (2011). Data were analyzed using structural equation modeling with SPSS 26 and AMOS 24.</span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:Aptos,sans-serif"><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Results:</span></span></b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""> The results showed that behavioral/motivational inhibition (&beta; = 0.63), behavioral/motivational activation (&beta; = 0.62), and experiential avoidance (&beta; = 0.50) had direct effects on craving. In addition, behavioral/motivational inhibition (&beta; = 0.53) and behavioral/motivational activation (CR = 0.59) had direct effects on experiential avoidance. Regarding indirect effects, the analysis of indirect effects showed that behavioral/motivational inhibition (&beta; = 0.80) and behavioral/motivational activation (&beta; = 0.79) had significant indirect effects on craving through experiential avoidance (p < 0.001).</span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:Aptos,sans-serif"><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Discussion and conclusion:</span></span></b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""> Behavioral/motivational brain systems lead to increased craving in individuals with substance dependence undergoing methadone maintenance treatment through increased experiential avoidance.</span></span></span></span></span></span><br> &nbsp; ,ولع مصرف,سیستم‌های مغزی/رفتاری,اختلالات مرتبط با مواد,متادون ,Craving,Behavioral Brain Systems,Substance-Related Disorders,Methadone 0 0 http://sjfm.ir/browse.php?a_code=A-10-2385-1&slc_lang=fa&sid=1 Zahra Shekari زهرا شکاری zahra.shekari2192@iau.ac.ir No Department of Psychology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran گروه روانشناسی، واحد ارسنجان، دانشگاه آزاد اسلامی، ارسنجان، ایران Akbar Rezai Fard اکبر رضایی فرد a.rezaieefard@cfu.ac.ir Yes Department of Psychology and Counseling Education, Farhangian University, P.O. Box 889-14665, Tehran, Iran. گروه آموزش روانشناسی و مشاوره ،دانشگاه فرهنگیان، صندوق پستی889-14665تهران، ایران Sakineh Karimi سکینه کریمی 2410712908@iau.ir No Department of Psychology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran. گروه روانشناسی، واحد ارسنجان، دانشگاه آزاد اسلامی، ارسنجان، ایران