[Home ] [Archive]   [ فارسی ]  
Main Menu
Home::
Journal Information::
About the Journal
Aims & Scopes
Editorial Board
Indexing & Abstracting
Archive::
All Issues
Current Issue
For Authors::
Authors' Guide
Reference Guide
Authorship Criteria
Submit an Article
For Reviewers::
Reviewing Policy
Principles of Transparency::
Publication Ethics Statement
Research Ethics Statement
Open Access Statement
Copyright
Contact us::
::
Search in website

Advanced Search
..
Licenses

AWT IMAGE

Attribution-NonCommercial
CC BY-NC

AWT IMAGE

Open Access Publishing

AWT IMAGE

Prevent Plagiarism

AWT IMAGE
..
:: Volume 23, Issue 4 (2018) ::
Iran J Forensic Med 2018, 23(4): 282-290 Back to browse issues page
Identifying Single-Nucleotide Polymorphisms (SNP) Effective in Face and Scull Identification
Afshin KHara1 , Abdullah Sajjadian 2
1- Najah Identification Center, Tehran, Iran
2- Molecular Genetics Department, Najah Identification Center, Tehran, Iran
Abstract:   (12494 Views)
Background: In recent years new technics and molecular genetic methods have been offered for face and scull identification in legal and criminal cases which simplify the assessment of individual characteristics like eye color, hair and skin. The technology of face identification by DNA molecule, studies the effective molecular markers in face and scull identification using the whole genome sequencing. 
Materials and Methods: This article studies the identification of the size and shape of face and scull using the imaging and molecular technology through scientific journals on NCBI and the ones published at Elsevier and Nature during 2010 to 2017.
Findings: The research showed that using the Next Generation Sequencing Platform machines, marks how POU2F3, OCA2, SLC24A4 and HERC2 have significant relationship with European and Asian population’s melanin that is responsible for the hair and skin color. The research also showed that single-nucleotide polymorphism changes in EDAR, DSHS2, FGFR1, PAX3 and COL17A1 is related to the morphology change and different people’s scull structure. 
Conclusion: Discovering the effective genes that form the melanin and shape of the face and scull will help us solve crimes using the biologic remains in crime scenes. 
Keywords: Single-Nucleotide Polymorphism, Next Generation Sequencing, Face and Scull Identifications, Molecular Markers
Full-Text [PDF 1120 kb]   (9802 Downloads)    
Type of Article: Research Article | Subject: Identification
Received: 2018/03/3 | Revised: 2018/03/20 | Accepted: 2018/03/3 | ePublished: 2018/03/3
References
1. Bouakaze C, Keyser C, Crubézy E, Montagnon D, Ludes B. Pigment phenotype and biogeographical ancestry from ancient skeletal remains: inferences from multiplexed autosomal SNP analysis. Int J Legal Med, 2009;123(4):315-25. [DOI] [PubMed]
2. Haselhuhn MP, Wong EM, Ormiston ME. Self-fulfilling prophecies as a link between men’s facial width-to-height ratio and behavior. PLoS One, 2013;8(8):p. e72259. [DOI] [PubMed]
3. Gupta S, Markey MK, Bovik AC. Anthropometric 3D face recognition. ‎Int J Comput Vis. 2010;90(3):331-49. [DOI]
4. Hennessy RJ, Baldwin PA, Browne DJ, Kinsella A, Waddington JL. Three-dimensional laser surface imaging and geometric morphometrics resolve frontonasal dysmorphology in schizophrenia. Biol Psychiatry. 2007;61(10):1187-94. [DOI] [PubMed]
5. Hennessy RJ, McLearie S, Kinsella A, Waddington JL. Facial surface analysis by 3D laser scanning and geometric morphometrics in relation to sexual dimorphism in cerebral–craniofacial morphogenesis and cognitive function. J Anat. 2005;207(3):283-95. [DOI] [PubMed]
6. Paternoster L, Zhurov AI, Toma AM, Kemp JP, Pourcain BS, Timpson NJ, et al. Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position. Am J Hum Genet. 2012;90(3):478-85. [DOI] [PubMed]
7. Fagertun J, Wolffhechel K, Pers TH, Nielsen HB, Gudbjartsson D, Stefansson H, et al. Predicting facial characteristics from complex polygenic variations. Forensic Sci Int Genet. 2015;19:263-8. [DOI] [PubMed]
8. Kayser M, Schneider PM. DNA-based prediction of human externally visible characteristics in forensics: motivations, scientific challenges, and ethical considerations. Forensic Sci Int Genet. 2009;3(3):154-61. [DOI] [PubMed]
9. Budowle B, van Daal A. Extracting evidence from forensic DNA analyses: Future molecular biology directions. Biotechniques. 2009;46(5):339. [DOI] [PubMed]
10. Valenzuela RK, Henderson MS, Walsh MH, Garrison NA, Kelch JT, Cohen‐Barak O, et al. Predicting phenotype from genotype: normal pigmentation. J Forensic Sci. 2010;55(2):315-22. [DOI] [PubMed]
11. Hrdlička A. Anthropometry. Am J Phys Anthropol, 1920;3(1):147–73. [DOI]
12. Douglas TS. Image processing for craniofacial landmark identification and measurement: a review of photogrammetry and cephalometry. Comput Med Imaging Graph. 2004;28(7):401-9. [DOI] [PubMed]
13. Adhikari K, Fuentes-Guajardo M, Quinto-Sánchez M, Mendoza-Revilla J, Chacón-Duque JC, Acuña-Alonzo V, et al. A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. Nat Commun. 2016;7:11616. [DOI] [PubMed]
14. Liu F, Van Der Lijn F, Schurmann C, Zhu G, Chakravarty MM, Hysi PG, et al. A genome-wide association study identifies five loci influencing facial morphology in Europeans. PLoS genetics. 2012;8(9):e1002932. [DOI] [PubMed]
15. Adel M, Yamaguchi T, Tomita D, Nakawaki T, Kim Y-I, Hikita Y, et al. Contribution of FGFR1 Variants to Craniofacial Variations in East Asians. PloS one. 2017;12(1):e0170645. [DOI] [PubMed]
16. Butler JM, Coble MD, Vallone PM. STRs vs. SNPs: thoughts on the future of forensic DNA testing. Forensic Sci Med Pathol. 2007;3(3):200-5.
17. Phillips C, Lareu M, Sanchez J, Brion M, Sobrino B, Morling N, Schneider P, Carracedo A. Selecting single nucleotide polymorphisms for forensic applications. Int Congr Ser. 2004;1261:18-20. Elsevier.
18. Butler JM, Budowle B, Gill P, Kidd K, Phillips C, Schneider P, et al. Report on ISFG SNP panel discussion. Forensic Science International: Forensic Sci Int Genet. 2008;1(1):471-2. [DOI]
19. Branicki W, Liu F, van Duijn K, Draus-Barini J, Pośpiech E, Walsh S, et al. Model-based prediction of human hair color using DNA variants. Hum Genet. 2011;129(4):443-54. [DOI] [PubMed]
20. Han J, Kraft P, Nan H, Guo Q, Chen C, Qureshi A, et al. A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS genetics. 2008;4(5):e1000074.
21. Mackay TF, Stone EA, Ayroles JF. The genetics of quantitative traits: challenges and prospects. Nature Rev Genet. 2009;10(8):565-77. [DOI] [PubMed]
22. Pneuman A, Budimlija ZM, Caragine T, Prinz M, Wurmbach E. Verification of eye and skin color predictors in various populations. Legal Medicine. 2012;14(2):78-83. [DOI] [PubMed]
23. Paternoster L, Zhurov AI, Toma AM, Kemp JP, Pourcain BS, Timpson NJ, et al. Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position. Am J Hum Genet. 2012;90(3):478-85. [DOI] [PubMed]
24. Roper RJ, Baxter LL, Saran NG, Klinedinst DK, Beachy PA, Reeves RH. Defective cerebellar response to mitogenic Hedgehog signaling in Down’s syndrome mice. Proc Natl Acad Sci USA. 2006;103(5):1452-6. [DOI] [PubMed]
25. Tzoulaki I, White IM, Hanson IM. PAX6 mutations: genotype-phenotype correlations. BMC genetics. 2005;6(1):27. [DOI] [PubMed]
26. Semin Cell Dev Biol. 2013;24(6-7):562-75. [DOI] [PubMed]
27. Begum F, Ghosh D, Tseng GC, Feingold E. Comprehensive literature review and statistical considerations for GWAS meta-analysis. Nucleic Acids Res. 2012;40(9):3777-84. [DOI] [PubMed]
28. Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature genetics. 2013;45(5):501. [DOI] [PubMed]
29. Costa e Silva APdAd, Antunes JLF, Cavalcanti MGP. Interpretation of mandibular condyle fractures using 2D-and 3D-computed tomography. Braz Dent J. 2003;14(3):203-8. [DOI]

XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
KHara A, Sajjadian A. Identifying Single-Nucleotide Polymorphisms (SNP) Effective in Face and Scull Identification. Iran J Forensic Med 2018; 23 (4) :282-290
URL: http://sjfm.ir/article-1-930-en.html
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 23, Issue 4 (2018) Back to browse issues page
مجله پزشکی قانونی ایران Iranian Journal of Forensic Medicine
Persian site map - English site map - Created in 0.06 seconds with 38 queries by YEKTAWEB 4645