fa بررسی خصوصیات دموگرافیک و بالینی بیماران مبتلا به تومورهای ناحیه پینه‌آل جراحی مغز و اعصاب Neurosurgery مقاله پژوهشی Research Article <div style="text-align: justify;"><span style="color:#000000;"><span style="font-family:yekanYW;"><span style="line-height:2;"><span style="font-size:16px;"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA">مقدمه: </span></b><span lang="AR-SA">غده</span> <span lang="AR-SA">پینه‌آل</span> <span lang="AR-SA">یک</span> <span lang="AR-SA">غده</span> <span lang="AR-SA">درون</span><span lang="fa">‌</span><span lang="AR-SA">ریز</span> <span lang="AR-SA">کوچک</span> <span lang="AR-SA">به</span> <span lang="AR-SA">شکل</span> <span lang="AR-SA">کاج</span> <span lang="AR-SA">است</span> <span lang="AR-SA">که</span> <span lang="AR-SA">در</span> <span lang="AR-SA">تنظیم</span> <span lang="AR-SA">بیولوژیکی</span> <span lang="AR-SA">ریتم</span> <span lang="AR-SA">شبانه‌روزی</span> <span lang="AR-SA">موثر میباشد</span><span lang="fa">. </span><span lang="AR-SA">تومورهای</span> <span lang="AR-SA">ناحیه</span> <span lang="AR-SA">پینه</span><span lang="fa">‌</span><span lang="AR-SA">آل</span> <span lang="AR-SA">تقریباً</span> <span lang="AR-SA">۳ تا ۱۱درصد</span> <span lang="AR-SA">از</span> <span lang="AR-SA">نئوپلاسم</span><span lang="fa">‌</span><span lang="AR-SA">های</span> <span lang="AR-SA">مغزی</span> <span lang="AR-SA">کودکان</span> <span lang="AR-SA">را</span> <span lang="AR-SA">تشکیل</span> <span lang="AR-SA">می‌دهند. مطالعه حاضر با هدف تعیین خصوصیات دموگرافیک و بالینی بیماران مبتلا به تومورهای ناحیه پینه‌آل انجام شد.</span><span lang="fa"><span style="font-family:"B Mitra""></span></span></span></span><br> <span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA">روش</span><span lang="fa">‌</span></b><b><span lang="AR-SA"> بررسی: </span></b><span lang="AR-SA"><span style="background:white">این</span></span> <span lang="AR-SA"><span style="background:white">مطالعه</span></span> <span lang="AR-SA"><span style="background:white">از نوع</span></span> <span lang="AR-SA"><span style="background:white">توصیفی</span></span> <span lang="AR-SA"><span style="background:white">مقطعی</span></span> <span lang="AR-SA"><span style="background:white">بود</span></span> <span lang="AR-SA"><span style="background:white">که</span></span> <span lang="AR-SA"><span style="background:white">در</span></span> <span lang="AR-SA"><span style="background:white">سال</span></span><span lang="fa"><span style="background:white"> ۱۴۰۲ </span></span><span lang="AR-SA"><span style="background:white">انجام</span></span> <span lang="AR-SA"><span style="background:white">شد.</span></span><span lang="fa"><span style="background:white">۲۰ </span></span><span lang="FA"><span style="background:white">بیمار</span></span><span lang="AR-SA"><span style="background:white"> با تومور</span></span> <span lang="AR-SA"><span style="background:white">ناحیه پینه</span></span><span lang="fa"><span style="background:white">‌</span></span><span lang="AR-SA"><span style="background:white">آل بصورت سرشماری</span></span> <span lang="AR-SA"><span style="background:white">شناسایی شدند که در طی ۸ سال گذشته به بیمارستانهای شهر اصفهان (الزهرا، کاشانی، امام حسین) مراجعه نموده بودند.</span></span> <span lang="AR-SA"><span style="background:white">داده‌ها توسط چک‌لیست جمع‌آوری و در نرم‌افزار </span></span><span dir="LTR" style="background:white">SPSS</span> <span lang="FA"><span style="background:white">ویرایش ۲۲ مورد تحلیل قرار گرفتند.</span></span></span></span><br> <span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA">یافته‌ها: </span></b><span lang="AR-SA"><span style="background:white">۱۰ نفر (۵۰ درصد) از بیماران مرد و میانه سن بیماران در زمان عمل جراحی ۱۹.۲۵ سال (محدوده ۰.۱۶ تا ۶۶ سال) بود. اندازه متوسط تومور ۲۴ میلیمتر و از نظر بافت‌شناسی، </span></span><span lang="AR-SA" style="background:white">تومور سلول زایا </span><span lang="AR-SA"><span style="background:white">و تومور پارانشیم پینه‌آل به ترتیب</span></span> <span lang="AR-SA"><span style="background:white">۴۵ و ۲۵ درصد از نئوپلاسم‌های ناحیه پینه</span></span><span lang="fa"><span style="background:white">‌</span></span><span lang="AR-SA"><span style="background:white">آل</span></span> <span lang="AR-SA"><span style="background:white">را تشکیل داده بودند.۶۰ درصد از بیماران تحت</span></span> <span lang="AR-SA"><span style="background:white">رادیوتراپی</span></span> <span lang="AR-SA"><span style="background:white">قرار گرفته بودند.</span></span> <span lang="AR-SA"><span style="background:white">سن</span></span> <span lang="AR-SA"><span style="background:white">بالاتر</span></span> <span lang="AR-SA"><span style="background:white">و</span></span> <span lang="FA"><span style="background:white">عدم رادیوتراپی </span></span><span lang="AR-SA"><span style="background:white">فاکتورهای</span></span> <span lang="AR-SA"><span style="background:white">با تاثیر منفی</span></span> <span lang="AR-SA"><span style="background:white">بر</span></span> <span lang="AR-SA"><span style="background:white">بقا</span></span> <span lang="AR-SA"><span style="background:white">بودند</span></span><span lang="fa"><span style="background:white">.</span></span> <span lang="AR-SA"><span style="background:white">کمترین نرخ بقا در سال اول بود اما با افزایش تعداد سال‌های زندگی، نرخ بقا نیز افزایش یافته بود. </span></span></span></span></span></span></span></span></div> <pre dir="RTL" style="text-align: justify;"> <span style="color:#000000;"><span style="font-family:yekanYW;"><span style="line-height:2;"><span style="font-size:16px;"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA">نتیجه‌گیری: </span></b><span lang="AR-SA">از آنجا که بیماران مبتلا به تومورهای ناحیه پینه‌آل بیشتر در محدوده سنی جوان قرار داشتند و جوانان نیروهای مولد در هر جامعه هستند بنابراین بایستی اقدامات و راهکارهای مناسبی را برای بهبود وضعیت بیماران در بلندمدت اتخاذ نمود تا بتوان تعداد سال‌های زندگی توام با کیفیت مناسب را برای آنها افزایش داد.</span></span></span></span></span></span></span> </pre> <div style="text-align: justify;"><span style="line-height:2;"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><b><span dir="RTL" lang="fa" new="" roman="" style="font-family:" times="">Introduction:</span></b><span dir="RTL" lang="fa" new="" roman="" style="font-family:" times=""> The pineal gland is a small, pinecone-shaped endocrine gland that participates in the biological rhythm regulation of vertebrates. Tumors of the pineal region account for approximately 3&ndash;11% of pediatric brain neoplasms. The present study aimed to determine the demographic and clinical characteristics of patients with tumors in the pineal region.</span></span></span><br> <span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><b><span dir="RTL" lang="fa" new="" roman="" style="font-family:" times="">Methods:</span></b><span dir="RTL" lang="fa" new="" roman="" style="font-family:" times=""> This research was a cross-sectional descriptive study that was conducted in 2023. 20 people with pineal tumor were identified who had referred to the hospitals of Isfahan city, Iran (Al-Zahra, Kashani and Imam Hossein) during the last 8 years. Data were collected by checklist and described and analyzed in SPSS version 22 software.</span></span></span><br> <span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><b><span dir="RTL" lang="fa" new="" roman="" style="font-family:" times="">Results:</span></b><span dir="RTL" lang="fa" new="" roman="" style="font-family:" times=""> Ten of patients were males and The mean age of the patients at the time of surgery was 19.25 years (range: 16.0 to 66.0 years). Histologically, GCT and PPT comprised 45 % and 25% of pineal region neoplasms. The median tumor size was 24 mm. The rates of radiotherapy administration were 60%. older age, and lack of radiotherapy use were prognostic factors that negatively influence survival. The lowest survival rate was observed in the first year, but as the number of years of life increased, so did the survival rate.</span></span></span><br> <span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><b><span dir="RTL" lang="fa" new="" roman="" style="font-family:" times="">Conclusion:</span></b><span dir="RTL" lang="fa" new="" roman="" style="font-family:" times=""> Given that patients with tumors in the pineal region are predominantly in the young age group, and young individuals represent the productive workforce in any society, it is imperative to implement appropriate measures and strategies to enhance these patients&#39; long-term well-being. Implementing these measures and strategies will ultimately improve the overall quality of life for these patients over the years.</span></span></span></span></div> <span style="font-size:11pt"><span style="line-height:150%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:150%"><span style="font-family:"B Mitra""></span></span></span></b></span></span></span></span></span> تومور مغزی, پینه‌آل, بیماران Region, Tumors, Patients 151 156 http://sjfm.ir/browse.php?a_code=A-10-2254-1&slc_lang=fa&sid=1 Sajad parvar سجاد پرور sajadparvar2026@gmail.com 110031947532846009255 110031947532846009255 No School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran دانشکده پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران mehrdad esmaeilvandi مهرداد اسماعیلوندی arieltehrani7@gmail.com 110031947532846009256 110031947532846009256 No School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran دانشکده پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران Ali Riazi علی ریاضی aliriazi1353@gmail.com 110031947532846009257 0000000288497677 Yes Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran گروه جراحی مغز و اعصاب، دانشکده پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران