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A survey on cardiovascular manifestations with organophosphate poisoning on admission with other signs and symptoms of poisoning and outcome
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Abstract: (21701 Views) |
| Abstract
Background & Aim: Organophosphates poisoning are the second cause of death in poisoned patients in Isfahan Poisoning Center. However, early diagnosis and appropriate management significantly can reduce both complications and mortality. Cardiovascular toxicity is one of the common system which affectd in this poisoning. The aim of this study is assessment of cardiovascular signs and symptoms on admission in relation of other manifestation of poisoning and outcome.
Materials & Methods: One hundred patients with documented organophosphate poisoning (as determined by history and clinical manifestations) and with complete medical records were enrolled in this cross-sectional study and data were analyzed by SPSS software and Fisher ,chi-square tests.
Findings: Organophosphate poisoning occurred more commonly in men (70%) and the average age of patients was 26.5±13. The most common symptoms were muscarinic symptoms (Increased secretion) (70%) and the most common cardiovascular parameter was tachycardia (26%). There was a significant correlation between cardiovascular parameters and respiratory and muscarinic parameters. Also, there was a significant correlation between some cardiovascular parameters (such as bradycardia and arrhythmia) and the poisoning prognosis.
Conclusion: Our results show that patients with cardiovascular signs on admission such as bradycardia or arrhythmia have a more grave prognosis and because they may need close monitoring in ICU setting so this type of poisoned patient must be consult or refer to poisoning emergency department early. |
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| Keywords: Organophosphate, Muscarinic Symptoms, Nicotinic Manifestations, Bradycardia, Arrhythmia |
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Full-Text [PDF 686 kb]
(2362 Downloads)
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Type of Article: Research Article |
Subject:
Forensic Medicine
Received: 2009/03/18 | Revised: 2009/05/6 | Accepted: 2018/03/29 | ePublished: 2018/03/29
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