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:: Volume 23, Issue 4 (2018) ::
Ir J Forensic Med 2018, 23(4): 282-290 Back to browse issues page
Identifying Single-Nucleotide Polymorphisms (SNP) Effective in Face and Scull Identification
Afshin KHara1, Abdullah Sajjadian 2
1- Najah Identification Center, Tehran, Iran
2- Molecular Genetics Department, Najah Identification Center, Tehran, Iran
Abstract:   (8498 Views)
Background: In recent years new technics and molecular genetic methods have been offered for face and scull identification in legal and criminal cases which simplify the assessment of individual characteristics like eye color, hair and skin. The technology of face identification by DNA molecule, studies the effective molecular markers in face and scull identification using the whole genome sequencing. 
Materials and Methods: This article studies the identification of the size and shape of face and scull using the imaging and molecular technology through scientific journals on NCBI and the ones published at Elsevier and Nature during 2010 to 2017.
Findings: The research showed that using the Next Generation Sequencing Platform machines, marks how POU2F3, OCA2, SLC24A4 and HERC2 have significant relationship with European and Asian population’s melanin that is responsible for the hair and skin color. The research also showed that single-nucleotide polymorphism changes in EDAR, DSHS2, FGFR1, PAX3 and COL17A1 is related to the morphology change and different people’s scull structure. 
Conclusion: Discovering the effective genes that form the melanin and shape of the face and scull will help us solve crimes using the biologic remains in crime scenes. 
Keywords: Single-Nucleotide Polymorphism, Next Generation Sequencing, Face and Scull Identifications, Molecular Markers
Full-Text [PDF 1120 kb]   (7077 Downloads)    
Article Type: Original Research | Subject: Identification of NAJA's identity
Received: 2018/03/3 | Accepted: 2018/03/3 | Published: 2018/03/3
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KHara A, Sajjadian A. Identifying Single-Nucleotide Polymorphisms (SNP) Effective in Face and Scull Identification. Ir J Forensic Med. 2018; 23 (4) :282-290
URL: http://sjfm.ir/article-1-930-en.html

Volume 23, Issue 4 (2018) Back to browse issues page
مجله پزشکی قانونی ایران Iranian Journal of Forensic Medicine
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